Trauma
Freeze-dried plasma mitigates the dilution effects of a hemoglobin-based oxygen carrier (HBOC-201) in a model of resuscitation for hemorrhage and hemodilution
2019
Trauma
Citation
Meledeo MA, Peltier GC, McIntosh CS, Taylor AS, Bynum JA, Pusateri AE, Cap AP. Freeze-dried plasma mitigates the dilution effects of a hemoglobin-based oxygen carrier (HBOC-201) in a model of resuscitation for hemorrhage and hemodilution. J Trauma Acute Care Surg. 2019 Jul;87(1S Suppl 1):S83-S90. doi: 10.1097/TA.0000000000002317. PMID:31246911
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Selective aortic arch perfusion with fresh whole blood or HBOC-201 reverses hemorrhage-induced traumatic cardiac arrest in a lethal model of noncompressible torso hemorrhage
2019
Trauma
Citation
Hoops HE, Manning JE, Graham TL, McCully BH, McCurdy SL, Ross JD. Selective aortic arch perfusion with fresh whole blood or HBOC-201 reverses hemorrhage-induced traumatic cardiac arrest in a lethal model of noncompressible torso hemorrhage. J Trauma Acute Care Surg. 2019 Aug;87(2):263-273. doi: 10.1097/TA.0000000000002315. PMID:31348400
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Reassessment of the need for an oxygen carrier for the treatment of traumatic hemorrhage when blood is not an option
2019
Trauma
Citation
Pusateri AE, Glassberg E, Weiskopf RB. Reassessment of the Need for an Oxygen Carrier for the Treatment of Traumatic Hemorrhage When Blood is not an Option. Shock. 2019;52(1S Suppl 1):55‐59. doi:10.1097/SHK.0000000000001417
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Use of hemoglobin based oxygen carrier HBOC-021 (Hemopure) as a bridge during emergencies in patients unable to receive blood products: experience at a tertiary care center
2019
Trauma
Citation
Bari S, Rabinovich M, Curry M, et al. Use of hemoglobin based oxygen carrier HBOC-021 (Hemopure) as a bridge during emergencies in patients unable to receive blood products: experience at a tertiary care center. Blood. 2017;130(Suppl 1):4926
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Hypertonic HBOC-201 decreases neutrophil activation after hemorrhagic shock
2014
Trauma
Citation
Rivera-Chávez FA, Lu A, Liu MM, Abdalla A, Minei JP. Hypertonic HBOC-201 decreases neutrophil activation after hemorrhagic shock. J Invest Surg. 2014 Feb;27(1):14-20. doi: 10.3109/08941939.2013.826756. PubMed PMID: 24456255.
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Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood
2014
Trauma
Citation
Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood. Am J Emerg Med. 2014 Mar;32(3):248-55. doi: 10.1016/j.ajem.2013.11.045. Epub 2013 Dec 7. PMID:24418449 | PMCID:PMC4049234
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Experience with the use of Hemopure in the care of a massively burned adult
2014
Trauma
Citation
Lundy JB, Lewis CJ, Cancio LC, Cap AP. Experience with the use of Hemopure in the care of a massively burned adult. Int J Burns Trauma. 2014 Feb 22;4(1):45-8. eCollection 2014. PMID:24624314 | PMCID:PMC3945828
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Traumatic brain injury and severe uncontrolled haemorrhage with short delay pre-hospital resuscitation in a swine model.
2012
Trauma
Citation
Teranishi K, Scultetus A, Haque A, Stern S, Philbin N, Rice J, Johnson T, et al. Traumatic brain injury and severe uncontrolled haemorrhage with short delay pre-hospital resuscitation in a swine model. Injury. 2012 May;43(5):585-93. doi: 10.1016/j.injury.2010.09.042. Epub 2010 Oct 30. PMID:21036354
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New and future resuscitation fluids for trauma patients using hemoglobin and hypertonic saline
2012
Trauma
Citation
Galvagno SM Jr, Mackenzie CF. New and future resuscitation fluids for trauma patients using hemoglobin and hypertonic saline. Anesthesiol Clin. 2013 Mar;31(1):1-19. doi: 10.1016/j.anclin.2012.10.004. Epub 2012 Dec 6. Review. PMID:23351531
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The effect HBOC-201 and sodium nitrite resuscitation after uncontrolled haemorrhagic shock in swine
2012
Trauma
Citation
Moon-Massat P, Scultetus A, Arnaud F, Brown A, Haque A, Saha B, et al. The effect HBOC-201 and sodium nitrite resuscitation after uncontrolled haemorrhagic shock in swine. Injury. 2012 May;43(5):638-47. doi: 10.1016/j.injury.2010.10.013. Epub 2010 Nov 20. PMID:21094491
Link
Pre-hospital resuscitation with HBOC-201 and rFVIIa compared to HBOC-201 alone in uncontrolled hemorrhagic shock in swine
2012
Trauma
Citation
Haque A, Arnaud F, Teranishi K, Okada T, Kim B, Moon-Massat PF, et al. Pre-hospital resuscitation with HBOC-201 and rFVIIa compared to HBOC-201 alone in uncontrolled hemorrhagic shock in swine. Artif Cells Blood Substit Immobil Biotechnol. 2012 Feb;40(1-2):44-55. doi: 10.3109/10731199.2011.585615. Epub 2011 Aug 2. PMID:21806503
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A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma
2011
Trauma
Citation
Fitzgerald MC, Chan JY, Ross AW, Liew SM, Butt WW, Baguley D, Salem HH, Russ MK, Deasy C, Martin KE, Mathew JK, Rosenfeld JV. A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma. Med J Aust. 2011 May 2;194(9):471-3. PMID:21534906
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Vasoactive hemoglobin solution improves survival in hemodilution followed by hemorrhagic shock
2011
Trauma
Citation
Vázquez BY, Hightower CM, Martini J, Messmer C, Frienesenecker B, Corbels P, et al. Vasoactive hemoglobin solution improves survival in hemodilution followed by hemorrhagic shock. Crit Care Med. 2011 Jun;39(6):1461-6. doi: 10.1097/CCM.0b013e3182120cdb. PMID:21336111 | PMCID:PMC3318980
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Is there a role for hemopure in the prehospital setting?
2011
Trauma
Citation
Minei JP. Is there a role for hemopure in the prehospital setting? J Trauma. 2011 May;70(5 Suppl):S38-9. doi: 10.1097/TA.0b013e31821a5a09. Review. No abstract available. PMID:21841569
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A bovine hemoglobin-based oxygen carrier as pump prime for cardiopulmonary bypass: reduced systemic lactic acidosis and improved cerebral oxygen metabolism during low flow in a porcine model
2011
Trauma
Citation
McNeil JD, Propper B, Walker J, Holguin L, Evans L, Lee K, et al. A bovine hemoglobin-based oxygen carrier as pump prime for cardiopulmonary bypass: reduced systemic lactic acidosis and improved cerebral oxygen metabolism during low flow in a porcine model. J Thorac Cardiovasc Surg. 2011 Aug;142(2):411-7. doi: 10.1016/j.jtcvs.2010.11.017. PMID:21641005
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Amylase and lipase detection in hemorrhaged animals treated with HBOC-201
2011
Trauma
Citation
Arnaud F, McCarron R, Freilich D. Amylase and lipase detection in hemorrhaged animals treated with HBOC-201.
Artif Cells Blood Substit Immobil Biotechnol. 2011 Jun;39(3):155-61. doi: 10.3109/10731199.2010.516260. Epub 2010 Dec 21. PMID:21171938
Link
Hemoglobin-based oxygen carrier (HBOC-201) and escalating doses of recombinant factor VIIa (rFVIIa) as a novel pre-hospital resuscitation fluid in a swine model of severe uncontrolled hemorrhage
2011
Trauma
Citation
Scultetus A, Arnaud F, Kaplan L, Shander A, Philbin N, Rice J, McCarron R, et al. Hemoglobin-based oxygen carrier (HBOC-201) and escalating doses of recombinant factor VIIa (rFVIIa) as a novel pre-hospital resuscitation fluid in a swine model of severe uncontrolled hemorrhage. Artif Cells Blood Substit Immobil Biotechnol. 2011 Apr;39(2):59-68. doi: 10.3109/10731199.2010.501755. Epub 2010 Jul 20. PMID:20645681
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Nitroglycerin attenuates vasoconstriction of HBOC-201 during hemorrhagic shock resuscitation
2010
Trauma
Citation
Katz LM, Manning JE, McCurdy S, Sproule C, McGwin G Jr, Moon-Massat P, et al. Nitroglycerin attenuates vasoconstriction of HBOC-201 during hemorrhagic shock resuscitation. Resuscitation. 2010 Apr;81(4):481-7. doi: 10.1016/j.resuscitation.2009.12.015. Epub 2010 Jan 18. PMID:20080328
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Resuscitation with the hemoglobin-based oxygen carrier, HBOC-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury
2009
Trauma
Citation
Stern S, Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, et al. Resuscitation with the hemoglobin-based oxygen carrier, HBOC-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury. Shock. 2009 Jan;31(1):64-79. doi: 10.1097/SHK.0b013e3181778dc3. PMID:18497706
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Innate immune response after resuscitation with hemoglobin-based oxygen carrier and recombinant factor VIIA in uncontrolled hemorrhagic shock in a swine model
2008
Trauma
Citation
Malkevich NV, Dong F, Vandermolen CA, Philbin NB, Rice JP, Scultetus A, et al. Innate immune response after resuscitation with hemoglobin-based oxygen carrier and recombinant factor VIIA in uncontrolled hemorrhagic shock in a swine model. J Trauma. 2008 Jun;64(6):1498-510. doi: 10.1097/TA.0b013e3181454a05. PMID:18545114
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Management of hemorrhagic shock when blood is not an option
2008
Trauma
Citation
Mackenzie CF, Morrison C, Jaberi M, Genuit T, Katamuluwa S, Rodriguez A. Management of hemorrhagic shock when blood is not an option. J Clin Anesth. 2008 Nov;20(7):538-41. doi: 10.1016/j.jclinane.2008.05.012. Epub 2008 Nov 18. PMID:19019664
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Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation
2008
Trauma
Citation
Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, et al. Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation. J Neurosurg. 2008 Mar;108(3):575-87. doi: 10.3171/JNS/2008/108/3/0575. PMID:18312106
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Hemoglobin-based oxygen carrying compound-201 as salvage therapy for severe neuro- and polytrauma (Injury Severity Score = 27-41
2008
Trauma
Citation
Dudkiewicz M, Harpaul TA, Proctor KG. Hemoglobin-based oxygen carrying compound-201 as salvage therapy for severe neuro- and polytrauma (Injury Severity Score = 27-41). Crit Care Med. 2008 Oct;36(10):2838-48. doi: 10.1097/CCM.0b013e318186f6b3. PMID:18766094
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Hematologic effects of recombinant factor VIIa combined with hemoglobin-based oxygen carrier-201 for prehospital resuscitation of swine with severe uncontrolled hemorrhage due to liver injury
2008
Trauma
Citation
Arnaud F, Hammett M, Philbin N, Scultetus A, McCarron R, Freilich D. Hematologic effects of recombinant factor VIIa combined with hemoglobin-based oxygen carrier-201 for prehospital resuscitation of swine with severe uncontrolled hemorrhage due to liver injury. Blood Coagul Fibrinolysis. 2008 Oct;19(7):669-77. doi: 10.1097/MBC.0b013e3283089198. PMID:18832908
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Innate immune responses in Swine resuscitated from severe traumatic hemorrhagic shock with hemoglobin-based oxygen carrier-201
2007
Trauma
Citation
Hall C, Malkevich N, Handrigan M, Vandermolen C, Aranaud F, Hong J, et al. Innate immune responses in Swine resuscitated from severe traumatic hemorrhagic shock with hemoglobin-based oxygen carrier-201. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(3):259-74. PMID:17573626
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Hematology patterns after hemoglobin-based oxygen carrier resuscitation from severe controlled hemorrhage with prolonged delayed definitive care
2007
Trauma
Citation
Arnaud F, Fasipe D, Philbin N, Rice J, Flournoy WS, Ahlers S, et al. Hematology patterns after hemoglobin-based oxygen carrier resuscitation from severe controlled hemorrhage with prolonged delayed definitive care. Transfusion. 2007 Nov;47(11):2098-109. PMID:17958540
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Immune effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers (HBOC) in a swine model of severe controlled hemorrhagic shock
2007
Trauma
Citation
VanderMolen C, Malkevich N, Philbin N, Rice J, Collier S, Hall C, et al. Immune effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers (HBOC) in a swine model of severe controlled hemorrhagic shock. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(5):507-17. PMID:17922315
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Resuscitation following severe, controlled hemorrhage associated with a 24 h delay to surgical intervention in swine using a hemoglobin based oxygen carrier as an oxygen bridge to definitive care
2007
Trauma
Citation
Philbin N, Handrigan M, Rice J, McNickle K, McGwin G, Williams R, et al. Resuscitation following severe, controlled hemorrhage associated with a 24 h delay to surgical intervention in swine using a hemoglobin based oxygen carrier as an oxygen bridge to definitive care. Resuscitation. 2007 Aug;74(2):332-43. Epub 2007 Mar 23. PMID:17383073
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Resuscitation from hemorrhagic shock comparing standard hemoglobin-based oxygen carrier (HBOC)-201 versus 7.5% hypertonic HBOC-201
2007
Trauma
Citation
Rivera-Chavez FA, Huerta S, Brown R, York GB, Minei JP. Resuscitation from hemorrhagic shock comparing standard hemoglobin-based oxygen carrier (HBOC)-201 versus 7.5% hypertonic HBOC-201. J Trauma. 2007 Nov;63(5):1113-9. PMID:17993959
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Resuscitation from hemorrhagic shock with HBOC-201 in the setting of traumatic brain injury
2007
Trauma
Citation
Kerby JD, Sainz JG, Zhang F, Hutchings A, Sprague S, Farrokhi FR, et al. Resuscitation from hemorrhagic shock with HBOC-201 in the setting of traumatic brain injury. Shock. 2007 Jun;27(6):652-6. PMID:17505305
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Coagulation patterns following haemoglobin-based oxygen carrier resuscitation in severe uncontrolled haemorrhagic shock in swine
2006
Trauma
Citation
Arnaud F, Handrigan M, Hammett M, Philbin N, Rice J, Dong F, et al. Coagulation patterns following haemoglobin-based oxygen carrier resuscitation in severe uncontrolled haemorrhagic shock in swine. Transfus Med. 2006 Aug;16(4):290-302. PMID:16879158
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Systemic function, oxygenation and microvascular correlation during treatment of hemorrhagic shock with blood substitutes
2006
Trauma
Citation
Cheung AT, Duong PL, Driessen B, Chen PC, Jahr JS, Gunther RA. Systemic function, oxygenation and microvascular correlation during treatment of hemorrhagic shock with blood substitutes. Clin Hemorheol Microcirc. 2006;34(1-2):325-34. PMID:16543653
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Bovine polymerized hemoglobin (hemoglobin-based oxygen carrier-201) resuscitation in three swine models of hemorrhagic shock with militarily relevant delayed evacuation--effects on histopathology and organ function
2006
Trauma
Citation
Johnson T, Arnaud F, Dong F, Philbin N, Rice J, Asher L, et al. Bovine polymerized hemoglobin (hemoglobin-based oxygen carrier-201) resuscitation in three swine models of hemorrhagic shock with militarily relevant delayed evacuation--effects on histopathology and organ function. Crit Care Med. 2006 May;34(5):1464-74. PMID:16540964
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Bovine polymerized hemoglobin versus Hextend resuscitation in a swine model of severe controlled hemorrhagic shock with delay to definitive care
2006
Trauma
Citation
Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, et al. Bovine polymerized hemoglobin versus Hextend resuscitation in a swine model of severe controlled hemorrhagic shock with delay to definitive care. Shock. 2006 Sep;26(3):302-10. PMID:16912657
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Prehospital HBOC-201 after traumatic brain injury and hemorrhagic shock in swine
2006
Trauma
Citation
Patel MB, Feinstein AJ, Saenz AD, Majetschak M, Proctor KG. Prehospital HBOC-201 after traumatic brain injury and hemorrhagic shock in swine. J Trauma. 2006 Jul;61(1):46-56. PMID:16832248
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Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage
2006
Trauma
Citation
Dong F, Hall CH, Golech SA, Philbin NB, Rice JP, Gurney J, et al. Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage. Shock. 2006 Jan;25(1):50-5. PMID:16369186
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A hemoglobin-based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in a moderate severity hemorrhagic shock swine model with delayed evacuation
2005
Trauma
Citation
Philbin N, Rice J, Gurney J, McGwin G, Arnaud F, Dong F, et al. A hemoglobin-based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in a moderate severity hemorrhagic shock swine model with delayed evacuation. Resuscitation. 2005 Sep;66(3):367-78. PMID:16081200
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Resuscitation with a hemoglobin-based oxygen carrier after traumatic brain injury
2005
Trauma
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King DR, Cohn SM, Proctor KG. Resuscitation with a hemoglobin-based oxygen carrier after traumatic brain injury. J Trauma. 2005 Sep;59(3):553-60; discussion 560-2. PMID:16361895
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Effects of bovine polymerized hemoglobin on coagulation in controlled hemorrhagic shock in swine
2005
Trauma
Citation
Arnaud F, Hammett M, Asher L, Philbin N, Rice J, Dong F, et al. Effects of bovine polymerized hemoglobin on coagulation in controlled hemorrhagic shock in swine. Shock. 2005 Aug;24(2):145-52. PMID:16044085
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Prolonged low-volume resuscitation with HBOC-201 in a large-animal survival model of controlled hemorrhage
2005
Trauma
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Fitzpatrick CM, Biggs KL, Atkins BZ, Quance-Fitch FJ, Dixon PS, Savage SA, et al. Prolonged low-volume resuscitation with HBOC-201 in a large-animal survival model of controlled hemorrhage. J Trauma. 2005 Aug;59(2):273-81; discussion 281-3. PMID:16294065
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Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scavenging in a model of arterial hemorrhage
2004
Trauma
Citation
Fitzpatrick CM, Savage SA, Kerby JD, Clouse WD, Kashyap VS. Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scavenging in a model of arterial hemorrhage. J Am Coll Surg. 2004 Nov;199(5):693-701. PMID:15501108
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Hope for reducing SA's trauma deaths?
2004
Trauma
Citation
Bateman C. Hope for reducing SA's trauma deaths? S Afr Med J. 2004 Sep;94(9):728-9. No abstract available. PMID:15487829
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A hemoglobin based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus Hetastarch (HEX) in an uncontrolled liver injury hemorrhagic shock swine model with delayed evacuation
2004
Trauma
Citation
Gurney J, Philbin N, Rice J, Arnaud F, Dong F, Wulster-Radcliffe M, et al. A hemoglobin based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus Hetastarch (HEX) in an uncontrolled liver injury hemorrhagic shock swine model with delayed evacuation. J Trauma. 2004 Oct;57(4):726-38. PMID:15514525
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Low-volume resuscitation with a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) provides adequate tissue oxygenation for survival in a porcine model of controlled hemorrhage
2003
Trauma
Citation
York GB, Eggers JS, Smith DL, Jenkins DH, McNeil JD, Mueller D, et al. Low-volume resuscitation with a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) provides adequate tissue oxygenation for survival in a porcine model of controlled hemorrhage. J Trauma. 2003 Nov;55(5):873-85. PMID:14608160
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A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low-volume resuscitation fluids in a model of controlled hemorrhagic shock
2003
Trauma
Citation
Sampson JB, Davis MR, Mueller DL, Kashyap VS, Jenkins DH, Kerby JD. A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low-volume resuscitation fluids in a model of controlled hemorrhagic shock. J Trauma. 2003 Oct;55(4):747-54. PMID:14566133
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Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation
2003
Trauma
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Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM. Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation. Adv Exp Med Biol. 2003;530:311-7. PMID:14562727
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Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201
2003
Trauma
Citation
Knudson MM, Lee S, Erickson V, Morabito D, Derugin N, Manley GT. Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201. J Trauma. 2003 Feb;54(2):242-52. PMID:12579047
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HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury
2002
Trauma
Citation
Katz LM, Manning JE, McCurdy S, Pearce LB, Gawryl MS, Wang Y, Brown C; Carolina Resuscitation Research Group. HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury. Resuscitation. 2002 Jul;54(1):77-87. PMID:12104112
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Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine
2002
Trauma
Citation
Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, et al. Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine. Acad Emerg Med. 2002 Oct;9(10):969-76. PMID:12359531
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Selective aortic arch perfusion with hemoglobin-based oxygen carrier-201 for resuscitation from exsanguinating cardiac arrest in swine
2001
Trauma
Citation
Manning JE, Katz LM, Pearce LB, Batson DN, McCurdy SL, Gawryl MS, et al. Selective aortic arch perfusion with hemoglobin-based oxygen carrier-201 for resuscitation from exsanguinating cardiac arrest in swine.Crit Care Med. 2001 Nov;29(11):2067-74. PMID:11700396
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Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism
2001
Trauma
Citation
McNeil CJ, Smith LD, Jenkins LD, York MG, Josephs MJ. Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism. J Trauma. 2001 Jun;50(6):1063-75. PMID:11426122
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Potential of hemoglobin-based oxygen carriers in trauma patients
2001
Trauma
Citation
Arnoldo BD, Minei JP. Potential of hemoglobin-based oxygen carriers in trauma patients. Curr Opin Crit Care. 2001 Dec;7(6):431-6. Review. PMID:11805546
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Bovine hemoglobin-based oxygen carrier (HBOC-201) for resuscitation of uncontrolled, exsanguinating liver injury in swine. Carolina Resuscitation Research Group.
2000
Trauma
Citation
Manning JE, Katz LM, Brownstein MR, Pearce LB, Gawryl MS, Baker CC. Bovine hemoglobin-based oxygen carrier (HBOC-201) for resuscitation of uncontrolled, exsanguinating liver injury in swine. Carolina Resuscitation Research Group. Shock. 2000 Feb;13(2):152-9. PMID:10670846
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Administration of polymerized bovine hemoglobin improves survival in a rat model of traumatic shock
1999
Trauma
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Hayward R, Lefer AM. Administration of polymerized bovine hemoglobin improves survival in a rat model of traumatic shock. Methods Find Exp Clin Pharmacol. 1999 Jul-Aug;21(6):427-33. PMID:10445236