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Relative Efficacies of HBOC-201 and Polyheme to Increase Oxygen Transport Compared to Blood and Crystalloids

Normalization of hemoglobin-based oxygen carrier-201 induced vasoconstriction: targeting nitric oxide and endothelin

Absence of developmental toxicity in a canine model after infusion of a hemoglobin-based oxygen carrier: Implications for risk assessment

Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood

Crosslinked, polymerized, and PEG-conjugated hemoglobin-based oxygen carriers: clinical safety and efficacy of recent and current products

Reconstructing hemoglobin-based oxygen carriers

Blood alternative products: correction regarding Jehovah's Witnesses.

Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction

Prevention of the pulmonary vasoconstrictor effects of HBOC-201 in awake lambs by continuously breathing nitric oxide. Anesthesiology.

Haemoglobin-based oxygen carriers: is the benefit worth the risk?

HBOC-201: the multi-purpose oxygen therapeutic

HBOC-201, hemoglobin glutamer-250 (bovine), Hemopure (Biopure Corporation)

Metanalysis critical of blood alternative product challenged

Modern Cross-linking Strategies for Synthesizing Acellular Hemoglobin-Based Oxygen Carriers

Blood substitutes as pharmacotherapies in clinical practice

Artificial oxygen carriers: a current review

Hemoglobin-based O2 carrier O2 affinity and capillary inlet pO2 are important factors that influence O2 transport in a capillary

Effects of Hemopure on maximal oxygen uptake and endurance performance in healthy humans

Acute and long-term effects of modified hemoglobin (HBOC-201) in a rat model of hypertension and chronic kidney disease

Improvement of impaired microcirculation and tissue oxygenation by hemodilution with hydroxyethyl starch plus cell-free hemoglobin in acute porcine pancreatitis

Oxygen radical formation does not have an impact in the treatment of severe acute experimental pancreatitis using free cellular hemoglobin

A comparison of the acute hemodynamic and delayed effects of 50% exchange transfusion with two different cross-linked hemoglobin based oxygen carrying solutions and Pentastarch

Hemopure's process demonstrates TSE and viral clearance

Microcirculatory function and tissue damage is improved after therapeutic injection of bovine hemoglobin in severe acute rodent pancreatitis

Structural and functional characterization of glutaraldehyde-polymerized bovine hemoglobin and its isolated fractions

Enhanced central organ oxygenation after application of bovine cell-free hemoglobin HBOC-201

The effect of hemopure on coagulation in clinically relevant concentrations

Hope for reducing SA's trauma deaths?

The use of a hemoglobin-based oxygen-carrying solution (HBOC-201) for extracorporeal membrane oxygenation in a porcine model with acute respiratory distress syndrome

Detection of hemoglobin-based oxygen carriers in human serum for doping analysis: confirmation by size-exclusion HPLC

Detection of hemoglobin-based oxygen carriers in human serum for doping analysis: screening by electrophoresis

Confirmation and quantification of hemoglobin-based oxygen carriers in equine and human plasma by hyphenated liquid chromatography tandem mass spectrometry

Hemoglobin-based oxygen carrier HBOC-201 provides higher and faster increase in oxygen tension in skeletal muscle of anemic dogs than do stored red blood cells

The effect of the bovine hemoglobin oxygen therapeutic HBOC-201 on human neutrophil activation in vitro

The pharmacology of tissue oxygenation by biopure's hemoglobin-based oxygen carrier, Hemopure (HBOC-201)

Does lead interfere with hemoglobin-based oxygen carrier (HBOC) function? A pilot study of lead concentrations in three approved or tested HBOCs and oxyhemoglobin dissociation with HBOCs and/or bovine blood with varying lead concentrations

The HemoCue, a point of care B-hemoglobin photometer, measures hemoglobin concentrations accurately when mixed in vitro with canine plasma and three hemoglobin-based oxygen carriers (HBOC)

Effects of hemoglobin glutamer-250 (bovine) (HBOC-201, Hemopure) on coagulation testing

The polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) is not toxic to neural cells in culture

Blood product from cattle wins approval for use in humans

Haemoglobin-based erythrocyte transfusion substitutes

Oxygen therapeutics--current concepts

Bovine hemoglobin. HBOC-201 causes a reduction of the oxygen partial pressure in poststenotic skeletal muscle

Transcranial Doppler sonography mean flow velocity during infusion of ultrapurified bovine hemoglobin

Effects of a novel hemoglobin-based oxygen carrier on percent oxygen saturation as determined with arterial blood gas analysis and pulse oximetry

Hematologic effects of a novel hemoglobin-based oxygen carrier in normal male and female subjects

Hemoglobin-based oxygen carrier preserves submaximal exercise capacity in humans

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